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Hideo Ohta Selected Research

3- (4- (4- ((1- (2- chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid

3/2009LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites.
4/2004Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.
2/2004Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1.

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Hideo Ohta Research Topics

Disease

4Neoplasms (Cancer)
06/2012 - 02/2004
4Ascites
06/2012 - 02/2004
3Pancreatic Neoplasms (Pancreatic Cancer)
06/2012 - 02/2004
3Stomach Neoplasms (Stomach Cancer)
11/2008 - 12/2004
2Neoplasm Metastasis (Metastasis)
06/2012 - 11/2007
1Rheumatoid Arthritis
10/2008
1Rectal Neoplasms (Rectal Cancer)
11/2007

Drug/Important Bio-Agent (IBA)

7lysophosphatidic acidIBA
06/2012 - 02/2004
4Lysophosphatidic Acid ReceptorsIBA
06/2012 - 02/2004
33- (4- (4- ((1- (2- chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acidIBA
03/2009 - 02/2004
3LipidsIBA
10/2008 - 02/2004
2Small Interfering RNA (siRNA)IBA
03/2009 - 02/2004
13- (4- (4- ((1- (2- chlorophenyl)ethoxy)carbonylamino)- 3- methyl- 5- isoxazolyl)benzylsulfanyl)propanoic acid methyl esterIBA
06/2012
1Matrix Metalloproteinases (MMPs)IBA
06/2012
1Proteins (Proteins, Gene)FDA Link
03/2009
1Epidermal Growth Factor (EGF)IBA
03/2009
1Pertussis ToxinIBA
03/2009
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
10/2008
1Irinotecan (Camptosar)FDA LinkGeneric
11/2007
1Fluorouracil (Carac)FDA LinkGeneric
11/2007
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2006
1Biological ProductsIBA
01/2006
1Phospholipids (Phosphatides)FDA LinkGeneric
04/2004
1alkylglycerophosphoethanolamine phosphodiesteraseIBA
04/2004
1Lysophosphatidylcholines (Lysophosphatidylcholine)IBA
04/2004
1Messenger RNA (mRNA)IBA
02/2004
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
02/2004
1CytokinesIBA
02/2004

Therapy/Procedure

1Oral Administration
06/2012
1Gastrectomy
11/2008
1Drug Therapy (Chemotherapy)
11/2007
1Therapeutics
04/2004